Prevalencia de tuberculosis pulmonar resistente a medicamentos de primera línea en adultos atendidos en el Centro de Salud Pascuales, Zona 8, Distrito 09D08 de la ciudad de Guayaquil en el año 2023.

Abstract

Pulmonary tuberculosis is a major problem worldwide with high mortality rates each year. The main objective of this research was to identify the prevalence of pulmonary tuberculosis resistant to first-line drugs in adults treated at the Pascuales Health Center during the year 2023.the methodology used in this research is based on a descriptive, retrospective and cross-sectional design. The sample consisted of patients diagnosed with tuberculosis at the health center. The Information were collected through medical records. Cases with first-line drug-resistant tuberculosis were analyzed based on the proposed variables. The results indicated a significant prevalence of MDR/RR TB in men (66.7%) compared to women (33.3%). Regarding resistance to first-line antifungals in the studied population, (22.2%) presents resistance to rifampicin, (66.7%) resistance to isoniazid and rifampicin and (11.1%) resistance to rifampicin, isoniazid and ethambutol. Finally, the seriousness and the urgent need for more effective strategies to deal with pulmonary tuberculosis by improving diagnostic and treatment methods were highlighted. Resistance to first-line drugs and co-infection with HIV pose considerable challenges in the treatment and control of the disease.