Enfermedad inflamatoria intestinal en pacientes con psoriasis entre 18 y 60 años en el Hospital General del Norte de Guayaquil los Ceibos durante el período de enero de 2020 a junio de 2023.

Abstract

Introduction: Psoriasis and inflammatory bowel disease are chronic inflammatory diseases that respond to environmental, genetic and immunological factors. Inflammatory bowel disease (IBD) encompasses two diseases such as Crohn's disease (CD) and ulcerative colitis (UC). Psoriasis is a chronic inflammatory condition that impacts around 2-3% of the global population and is characterized by the presence of red, scaly plaques on the skin. IBD and psoriasis are directly associated, both in the pathogenic and genetic aspects, this translates into the increase in the prevalence of IBD in patients with psoriatic arthritis. Objective: To evaluate the importance of the evolution of inflammatory bowel disease in patients diagnosed with psoriasis. Methodology: A relational, retrospective, observational and cross-sectional study was carried out in the outpatient consultation area of the Gastroenterology and Dermatology service of the General Hospital of the North of Guayaquil Los Ceibos during the period from January 2020 to June 2023 in Guayaquil, Ecuador. We worked with a population of 790 patients with a diagnosis of psoriasis and IBD, a sample size calculation was performed and a sample of 259 patients was obtained whose medical records met the inclusion criteria. The following variables were considered: age, sex, type of IBD, Psoriasis Area Severity Index (PASI). The analysis was carried out according to the proposed objectives using the SPSS tool. Results: Inflammatory bowel disease occurred in 5.79% of the sample. The most frequent associated factor was obesity with 20.08%, a greater relationship was observed between the group of 46 to 60 years and the presence of IBD (p=0.024), the type of IBD with the highest percentage was ulcerative colitis with 20.08%, A greater relationship was observed between severe psoriasis and IBD (severe: >15 points), the evolution time of psoriasis was 6.73 years.XIII Conclusion: It was determined that the prevalence of IBD in patients with psoriasis was 5.79%, where ulcerative colitis had a higher percentage (73.3%).