Utilidad del AST to platelet ratio index (APRI score) como predictor del Síndrome de HELLP en embarazadas ingresadas en el Hospital Alfredo Paulson durante el periodo de enero del 2018 a enero del 2021.

Abstract

Introduction: APRI score is the division between aspartate aminotransferase and platelet level, it corresponds to a biochemical model usually used as a predictor for liver fibrosis and cirrhosis that at present has been associated with HELLP syndrome as a predictor of this pathology. This syndrome is characteristic of elevated liver enzymes, hemolysis, and decreased platelets. Objective: To determine the usefulness of the APRI score in patients with HELLP syndrome and the relationship with maternal and child complications. Methods & Materials: This is an observational, retrospective, analytical and comparative study, in which the clinical records of the patients admitted to the Alfredo Paulson Women's Hospital with a diagnosis of HELLP Syndrome were reviewed during the period from January 2018 to January 2021. Results: A total of 107 patients were studied with a mean age of 28, with a minimum age of 16 and a maximum age of 43. The most frequent maternal complication was uterine bleeding with an incidence of 29.91%, followed by acute renal failure with a value of 23.5 %. 59.81% of the newborns were premature. Conclusion: The application of the APRI Score presented a certain degree of utility in the prognosis of maternal complications of HELLP syndrome; however, it does not represent any predictive value in the development of neonatal complications.