Linfoma de Hodgkin variantes histológicas más frecuentes en pacientes pediátricos, Hospital del Niño Dr. Francisco de Icaza Bustamante, período 2016 a 2022.

Abstract

Hodgkin lymphoma (HL) is a malignant lymphoma with an impact that covers both the pediatric and adult populations. Cases occur in a bimodal distribution with a peak in the adolescent and young adult population. In pediatrics, the incidence of HL is 12.2 per million in children under 20 years of age, but 32 per million between 15 and 19 years of age, and the highest between 20 and 24 years old, with 45 per million. This disease presents histological variants and clinical characteristics that can influence its management and prognosis OBJECTIVE: to identify the most frequent histological variants of Hodgkin's lymphoma in patients at the Hospital del Niño Dr. Francisco de Icaza Bustamante period 2016 to 2022. METHODOLOGY: retrospective study, analytical and cross-sectional. RESULTS: 93 cases diagnosed during this time were collected, observing a predominance in male patients and in the mestizo population. The age distribution showed that the 6- to 10-year-old group was the most affected, highlighting the importance of paying attention to this cohort in early detection and disease management efforts. In addition, classical Hodgkin's lymphoma with its most common histological variant, nodular sclerosis, as well as nodular lymphocytic-predominant Hodgkin's lymphoma (nLPHL) were identified, which may influence the treatment and prognosis of patients. CONCLUSION: in the present study, classic Hodgkin lymphoma was the most frequent, of which its predominant histological variant was the nodular sclerosis type. Within the demographic factors we found that the predominant age was between 6 to 10 years, with gender the male is more affected.