Marcadores biológicos asociados a complicaciones en pacientes colecistectomizados de 30 a 60 años en el Hospital Básico IESS Durán, Durán – Ecuador en el período enero de 2019 a enero de 2023.

Abstract

Introduction: Cholecystectomy is a procedure that is used daily, electively or urgently, however, several patients with a morbid history or acute conditions such as cholecystitis are at risk of presenting complications. Objective: Establish the biological markers associated with complications in cholecystectomized patients aged 30 to 60 years at the IESS Duran Basic Hospital. Materials and Methods: Apply a retrospective, cross-sectional, observational research model with analytical and empirical methods. A random sample of 100 patients was considered. Results: The female sex was more frequent with 72%, and the most common age group was between 30 and 40 years. The indications for cholecystectomy were cholelithiasis (77%), choledocholithiasis (14%), and 9% between acute cholecystitis, acute biliary pancreatitis and suppurative cholangitis. There were 7% complications, including increased hospital stay, surgical wound infection, need for ERCP, and surgical reintervention. The biological markers associated with complications in cholecystectomized patients were CRP and AF, since they were shown to be statistically significant (p<0.05). There was only 1% mortality. Conclusion: Female sex and age between 30 and 40 years are the most frequent epidemiological data in patients undergoing cholecystectomy. The markers associated with complications were shown to be altered levels of CRP and alkaline phosphatase.