Factores predictivos de mortalidad en pacientes con SARS-CoV-2 hospitalizados en unidades criticas del hospital de niños Dr. Roberto Gilbert Elizalde durante el periodo marzo 2020 – marzo 2021

Abstract

Background: The different studies by SARS-CoV-2 in children indicated that children <1 year old and children with comorbidities may have a higher risk of severe disease progression (9). In relation to the clinical presentation, PIMS affects, above all, previously healthy patients, unlike acute COVID-19, in which greater severity is closely related to the existence of comorbidities (7,8). Ruan et al, showed age, the presence of underlying diseases, the presence of secondary infection and elevated inflammatory indicators in the blood as possible predictors of SARS-CoV-2 mortality (10). Objectives: To describe the predictive factors of mortality in patients with SARS-CoV-2 hospitalized in critical units of the Dr. Roberto Gilbert Elizalde Children's Hospital during the period March 2020 - March 2021. Methods: An observational, retrospective, cross-sectional investigation was carried out, and descriptive. The level of research was descriptive. Analysis: The Excel statistical package was used. The comparison of means was carried out by means of the association using Pearson's Chi Square. The cut-off probability of this study was set at (p < 0.05). The degree of statistical significance p chosen is <0.05. Results: During the study, significant differences were found between the patient's age, the PIM III score at admission and the outcome of the patient with SARS-CoV-2. Conclusions: The risk factors that increase the probability of death in pediatric patients affected by COVID-19 are not clearly defined. It has been seen that the association of comorbidities in both children and adults leads to an increase in the mortality rate and hospital stay in intensive care units. The PIM III did not prove to be a parameter that puts on alert in the case of COVID-19 patients who had to be admitted to the intensive care unit and its relationship with the evolution.