Efectividad del uso de Ibuprofeno y Paracetamol en el cierre del ductus arterioso persistente en neonatos prematuros durante septiembre de 2019 a febrero de 2020 en el Hospital General Norte de Guayaquil Los Ceibos.

Abstract

Objective of the study: To demonstrate the efficacy of Ibuprofen and Paracetamol as a treatment for closure of the patent ductus arteriosus in the Neonatology area at the Hospital General Norte de Guayaquil Los Ceibos during September 2019 to February 2020. Question / hypothesis: Are ibuprofen and paracetamol useful for the treatment of patent ductus arteriosus? There is correlation between the administration of ibuprofen or paracetamol and the closure of the patent ductus arteriosus. Research method: Descriptive studies with frequency tables were used, and correlational study with crossed tables and their critical distribution values, with chi square with Pearson's index. In addition, a Chi Square study was carried out with more degrees of freedom and percentage for sensitivity studies. Results: In the Chi Square study, there were 13 patients who did have a medical prescription with a positive resolution, patients who did have a prescription with NSAIDs with a negative resolution were 8. Patients who did not have a prescription with a positive resolution were 24 and patients who did not have a prescription and they had a negative resolution were 6. Conclusions and recommendations: It is concluded that there is no correlation between the administration of paracetamol or ibuprofen and the closure of the patent ductus arteriosus. That is, the expectant attitude is more useful for the same purpose according to this study. It is recommended to carry out a study with a larger population to reduce the alpha error and improve the reliability percentage.