Manifestaciones orales presentes en pacientes con cáncer bajo el tratamiento de cetuximab en SOLCA, semestre A 2019.

Abstract

Introduction: oral manifestations occur in a large percentage in the treatment of chemotherapy and radiotherapy which deteriorate the quality of life of patients during cancer therapy. Objective: To demonstrate the relationship of oral manifestations in cancer patients under the treatment of cetuximab. Materials and methods: The universe was 232 cancer patients, of which we included patients older than 18 years under the treatment of cetuximab and whose medical records are complete obtaining a sample of 75 medical record. Results: The statistical data of 75 patients was made according to the inclusion criteria of the sample of which 42.76% are women and 57.33% are men. The study shows that patients receiving cetuximab and radiotherapy have stomatological lesions 44% Xerostomia, 77.33% candidiasis and 82.67% Mucositis, those receiving cetuximab only presented candidiasis in 1.33% and those who only received radiotherapy, 1.33% presented Xerostomia and Mucositis. Discussion: In the present study we found a higher prevalence of stomatological lesions associated with cetuximab as shown by author G Estrada in his study. As for mucositis, there was a higher percentage in grade I mucositis, which is consistent with the author Ocampo. Conclusion: In the present study it was concluded that cancer therapy presents a high toxicity in general of cancer patients, stomatological lesions being very common adverse effects in patients under the treatment of cetuximab alone or in combination with radiotherapy.