Características clínicas y tratamiento empleado de lupus eritematoso sistémico en pacientes atendidos en el Hospital Teodoro Maldonado Carbo en el año 2016.

Abstract

Introduction: Systemic Lupus Erythematosus (SLE) is an autoimmune and chronic disease, with a multisystemic compromise, from mild to severe or fatal conditions, making it difficult to diagnose. Objective: To describe the clinical characteristics and treatment used for SLE in patients treated at Hospital Teodoro Maldonado Carbo in 2016. Materials and methods: Retrospective cross-sectional descriptive observational study. The data collection was done in Microsoft Excel by reviewing the evolutions in the AS400 system and the statistical analysis in the SPSS program. Results: For the study, 274 patients were analyzed, of which 87.8% were female, the age range was 14 years to 84 years with an average of 45.55 years and a mode of 43 years. Within the clinical manifestations in order of frequency were serological (64.39%), hematological (52.16%), cutaneous-mucosal (51.44%), renal (44.60%), etc. Drugs used were corticoids (75.54%), chloroquine (52.52%), hydroxychloroquine (41.73%), mycophenolate mofetil (38.13%), NSAIDs (23.02%), etc. The SLEDAI score was performed in 31.3% of the patients, from which the mean was 4.61, the mode 2, the range between 0 and 25. Conclusions: the SLE is more frequent in the female sex, higher prevalence was found between 30 and 60 years of age. Serological, hematological, cutaneous-mucous, renal manifestations were the most frequent, as well as in the most used treatment was corticosteroids, antimalarials, mycophenolate mofetil and NSAIDs.